Intravitreal injections are commonly used to treat retinal diseases such as diabetic retinopathy, macular degeneration and retinal vein occlusion. These diseases often cause blindness and should be treated as early and as thoroughly as possible. The ANTI-VEGF are injected directly into the eye to help patients maintain their baseline vision and keep vision loss at a minimum. Many patients often see an improvement in their vision from these injections as well.
Intraocular injections are especially effective in treating wet age-related macular degeneration, which, although less common than the dry form, accounts for more than 90% of blindness caused by the disease.

This procedure is performed in the operating room and requires only a local anesthetic. Before the medication is injected, the eye is numbed with anesthetic eye drops to help minimize discomfort. The eye is then cleaned with an antiseptic solution and held open with an eye speculum. The ANTI-VEGF is then injected directly into the eye, in the vitreous. Intraocular injections are usually given more than once to maintain eye health in patients with degenerative eye diseases. It gives no pain.